Description:
| * Indications: |
| It is indicated for the treatment of Parkinson’s disease and syndrome. It is useful in relieving many of the symptoms |
| of parkinsonism, particularly rigidity and bradykinesia. Sinemet frequently is helpful in the management of tremor, dysphagia, |
| sialorrhea, and postural instability associated with Parkinson’s disease and syndrome. When therapeutic response of levodopa |
| alone is irregular, and signs and symptoms of Parkinson’s disease are not evenly controlled throughout the day, |
| substitution of Sinemet usually is effective in reducing fluctuations in response. By reducing certain adverse reactions |
| produced by levodopa alone, Sinemet permits more patients to obtain adequate relief of the symptoms of Parkinson’s disease. |
| Sinemet is also indicated for patients with Parkinsonism who are taking vitamin preparations that contain pyridoxine HCl (Vit.B6). |
| * Dosage & Administration: |
| The optimum daily dosage of Sinemet must be determined by careful titration in each patient. Sinemet tablets are |
| available in a 1:10 ratio of carbidopa to levodopa (Sinemet 25/250). Each tablet of Sinemet is designed to divide in half with |
| minimal pressure. |
| * To be dispensed only by or on the prescription of a physician. |
| * Store in a dry place, at temperature between 15 – 30 degrees C, Protect from light. |
| * Manufactured by: Merck Sharp & Dohme (MSD) – Italy. |
